神經(jīng)遞質(zhì)受體PCR芯片可用于研究參與神經(jīng)遞質(zhì)合成,吸收,運(yùn)輸,和神經(jīng)遞質(zhì)受體信號等生物學(xué)過程的84個關(guān)鍵基因的表達(dá)。該芯片包含多種神經(jīng)遞質(zhì)的對應(yīng)的受體,包括乙酰膽堿,苯二氮,多巴胺,伽馬氨基丁酸(GABA),谷氨酸脂,5-羥色胺,生長激素抑素和神經(jīng)肽。此外,還包含調(diào)控神經(jīng)遞質(zhì)水平的基因。利用實時定量PCR,研究者可以方便并且可信地對與神經(jīng)系統(tǒng)相關(guān)的基因進(jìn)行同時檢測。 Adrenergic Receptors: Alpha Adrenergic: ADRA1A, ADRA1D, ADRA2A. Beta Adrenergic: ADRB2, ADRB3. Cholinergic ReceptorsMuscarinic: CHRM1, CHRM4, CHRM5. Nicotinic: CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNE. Dopaminergic Receptors: DRD1, DRD2, DRD5. GABAergic Receptors: GABAA: GABRA1, GABRA2, GABRA4, GABRA5, GABRA6, GABRB1, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRQ. GABAB: GABBR1, GABBR2. GABAC: GABRR1, GABRR2. Glutamate Receptors: AMPA Receptors: GRIA1, GRIA2, GRIA3. Kainate Receptors: GRIK1, GRIK2, GRIK4, GRIK5. NMDA Receptors: GRIN1, GRIN2A, GRIN2B, GRIN2C. Metabotropic Receptors: GRM1, GRM3, GRM4, GRM5, GRM6, GRM7, GRM8. Serotonin Receptors: HTR1A, HTR1B, HTR1D, HTR1F, HTR2A, HTR2C, HTR3A, HTR4, HTR7. Other Neurotransmitter Receptors: Vasopressin Receptor: AVPR1A, AVPR1B. Histamine Receptor: HRH1, HRH4. Neuropeptide Y: NPY2R, NPY5R. Somatostatin: SSTR1, SSTR2, SSTR4. Substance P (Neurokinin) Receptor: TACR1, TACR2, TACR3. Other Receptors: BRS3, CCKBR, CNR1, GCGR, GRPR, HCRTR2, NTSR2, OXTR, PROKR2 (GRP73L1), SCTR, TSPO (BZRP). |