地區(qū): | 上海 |
簡介: | 上海 |
提供商: | SABio |
服務名稱: | PCR芯片 |
先天免疫與適應性免疫PCR芯片可檢測細菌感染和壞血癥引起的宿主反應相關的84個基因。芯片包含IL-1R與Toll-like Receptor(TLR)信號通路相關的基因,如檢測病原體的IL-1R和TLR基因。芯片也包含了與抗菌宿主防御相關的基因,如監(jiān)測細菌急性期反應、補體激活、炎癥反應和抗菌體液反應等相關基因。另外,還包括了先天免疫應答和感染性休克相關的基因。通過實時定量PCR的方法,研究者即能夠利用該芯片簡單可靠地同時檢測先天免疫和適應性免疫應答相關的基因表達。 Innate Immunity: Pattern Recognition Receptors: DDX58 (RIG-I), NLRP3, NOD1 (CARD4), NOD2, TLR1, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, TLR8, TLR9. Cytokines: CCL2 (MCP-1), CCL5 (RANTES), CSF2 (GM-CSF), CXCL10, IFNA1, IFNB1, IL18, IL1A, IL1B, IL2, IL8, TNF. Other Genes: APCS, C3, CASP1 (ICE), CD14, CD4, CD40 (TNFRSF5), CD40LG (TNFSF5), CD8A, CRP, HLA-A, HLA-E, IL1R1, IRAK1, IRF3, IRF7, ITGAM, LY96 (MD-2), LYZ, MAPK1 (ERK2), MAPK8 (JNK1), MBL2, MPO, MX1, MYD88, NFKB1, NFKBIA (I?Ba/Mad3), STAT1, TICAM1 (TRIF), TRAF6. Adaptive Immunity: Th1 Markers/Immune Response: CCR5, CD80, CXCR3, IFNG, IL18, IL23A, SLC11A1, STAT4, TBX21, TLR4, TLR6. Th2 Markers/Immune Response: CCR4, CCR8, CD86, GATA3, IFNB1, IL10, IL13, IL18, IL4, IL5, IL6, NOD2, STAT6. Th17 Markers: CCR6, IL17A, RORC, STAT3. Treg Markers: CCR4, CCR8, FOXP3, IL10. T Cell Activation: CD80, CD86, ICAM1, IFNG, IL23A, IL6, SLC11A1. Cytokines: CCL2 (MCP-1), CCL5 (RANTES), CSF2 (GM-CSF), CXCL10 (INP10), IFNA1, IFNG, IL10, IL13, IL17A, IL18, IL2, IL23A, IL4, IL5, IL6, IL8, TNF. Other Genes: CD4, CD40 (TNFRSF5), CD40LG (TNFSF5), CD8A, CRP, FASLG (TNFSF6), HLA-A, IFNAR1, IFNGR1, IL1B, IL1R1, IRF3, IRF7, ITGAM, JAK2, MAPK8 (JNK1), MBL2, MX1, NFKB1, RAG1, STAT1. Humoral Immunity: C3, CCL2 (MCP-1), CCR6, CRP, IFNB1, IFNG, IL6, MBL2, NOD2, TNF. Inflammatory Response: APCS, C3, CCL5 (RANTES), CRP, FOXP3, IL1A, IL1B, IL4, IL6, MBL2, STAT3, TNF. Defense Response to Bacteria: IFNB1, IFNG, IL23A, IL6, LYZ, MBL2, MYD88, NOD1 (CARD4), NOD2, SLC11A1, TLR1, TLR3, TLR4, TLR6, TLR9, TNF. Defense Response to Viruses: CD4, CD40 (TNFRSF5), CD86, CD8A, CXCL10 (INP10), DDX58 (RIG-I), HLA-A, IFNAR1, IFNB1, IL23A, IL6, IRF3, NLRP3, TICAM1 (TRIF), TLR3, TLR7, TLR8, TYK2. |