凋亡PCR芯片96孔板 Apoptosis PCR Array 96HT

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凋亡PCR芯片96孔板 Apoptosis PCR Array 96HT

凋亡PCR芯片96孔板 Apoptosis PCR Array 96HT
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地區(qū)：上海
簡(jiǎn)介：上海
提供商：SABio
服務(wù)名稱(chēng)：PCR芯片
凋亡PCR芯片可用于研究參與細(xì)胞程序性死亡的84個(gè)關(guān)鍵基因的表達(dá)。細(xì)胞凋亡在正常生物過(guò)程中發(fā)揮重要作用，如分化、發(fā)育和體內(nèi)平衡。應(yīng)激反應(yīng)，如熱休克、缺血、非折疊蛋白和病毒感染，會(huì)引起細(xì)胞嚴(yán)重受損甚至細(xì)胞凋亡。細(xì)胞凋亡經(jīng)常導(dǎo)致不可控的細(xì)胞生長(zhǎng)，如腫瘤形成和癌癥；同時(shí)腫瘤壞死因子（TNF）受體也會(huì)通過(guò)激活FADD和其他死亡受體蛋白引起凋亡。這一芯片包含了TNF配體及受體、bcl-2、半胱天冬酶、IAP、TRAF、CARD、死亡域、死亡效應(yīng)域、CIDE家族，以及參與p53和DNA損傷通路的基因。研究這些基因的表達(dá)有助于確定在生物模型和細(xì)胞模型中的細(xì)胞機(jī)制。通過(guò)實(shí)時(shí)定量PCR的方法，研究者即能夠利用該芯片簡(jiǎn)單可靠地同時(shí)檢測(cè)細(xì)胞凋亡相關(guān)基因的表達(dá)。
 
Apoptosis PCR ArrayHumanGene ExpressionPAHS-012Z
Apoptosis PCR ArrayHumanGene Expression 384HTPAHS-3012Z
Apoptosis PCR ArrayMouseGene ExpressionPAMM-012Z
Apoptosis PCR ArrayMouseGene Expression 384HTPAMM-3012Z
Apoptosis PCR ArrayRatGene ExpressionPARN-012Z
Apoptosis PCR ArrayRatGene Expression 384HTPARN-3012Z
Apoptosis PCR ArrayRhesus MacaqueGene ExpressionPAQQ-012Z
Apoptosis PCR ArrayChickenGene ExpressionPAGG-012Z
Apoptosis PCR ArrayPigGene ExpressionPASS-012Z
 
Induction of Apoptosis: Death Domain Receptors: CRADD, FADD, TNF, TNFRSF10B (DR5). DNA Damage: ABL1, CIDEA, CIDEB, TP53, TP73. Extracellular Signals: CFLAR (CASPER), DAPK1, TNFRSF25 (DR3). Other: BAD, BAK1, BAX, BCL10, BCL2L11, BID, BIK, BNIP3, BNIP3L, CASP1 (ICE), CASP10 (MCH4), CASP14, CASP2, CASP3, CASP4, CASP6, CASP8, CD27 (TNFRSF7), CD70 (TNFSF7), CYCS, DFFA, DIABLO (SMAC), FAS (TNFRSF6), FASLG (TNFSF6), GADD45A, HRK, LTA (TNFB), NOD1 (CARD4), PYCARD (TMS1/ASC), TNFRSF10A, TNFRSF9, TNFSF10 (TRAIL), TNFSF8, TP53BP2, TRADD, TRAF3. Anti-Apoptosis: AKT1, BAG1, BAG3, BAX, BCL2, BCL2A1 (Bfl-1/A1), BCL2L1 (BCL-X), BCL2L10, BCL2L2, BFAR, BIRC3 (c-IAP1), BIRC5, BIRC6, BNIP2, BNIP3, BNIP3L, BRAF, CD27 (TNFRSF7), CD40LG (TNFSF5), CFLAR (CASPER), DAPK1, FAS (TNFRSF6), HRK, IGF1R, IL10, MCL1, NAIP (BIRC1), NFKB1, NOL3, RIPK2, TNF, XIAP (BIRC4). Regulation of Apoptosis: Negative Regulation: BAG1, BAG3, BCL10, BCL2, BCL2A1 (Bfl-1/A1), BCL2L1(BCL-X), BCL2L10, BCL2L2, BFAR, BIRC2 (c-IAP2), BIRC3 (c-IAP1), BIRC6, BNIP2, BNIP3, BNIP3L, BRAF, CASP3, CD27 (TNFRSF7), CD40LG (TNFSF5), CFLAR (CASPER), CIDEA, DAPK1, DFFA, FAS (TNFRSF6), IGF1R, MCL1, NAIP (BIRC1), NOL3, TP53, TP73, XIAP (BIRC4). Positive Regulation: ABL1, AKT1, BAD, BAK1, BAX, BCL2L11, BID, BIK, BNIP3, BNIP3L, CASP1 (ICE), CASP10 (MCH4), CASP14, CASP2, CASP4, CASP6, CASP8, CD40 (TNFRSF5), CD70 (TNFSF7), CIDEB, CRADD, FADD, FASLG (TNFSF6), HRK, LTA (TNFB), LTBR, NOD1 (CARD4), PYCARD (TMS1/ASC), RIPK2, TNF, TNFRSF10A, TNFRSF10B (DR5), TNFRSF25 (DR3), TNFRSF9, TNFSF10 (TRAIL), TNFSF8, TP53, TP53BP2, TRADD, TRAF2, TRAF3. DEATH Domain Proteins: CRADD, DAPK1, FADD, TNFRSF10A, TNFRSF10B (DR5), TNFRSF11B, TNFRSF1A, TNFRSF1B, TNFRSF21, TNFRSF25 (DR3), TRADD. Caspases and Regulators: Caspases: CASP1 (ICE), CASP10 (MCH4), CASP14, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9, CFLAR (CASPER), CRADD, PYCARD (TMS1/ASC). Caspase Activators: AIFM1 (PDCD8), APAF1, BAX, BCL2L10, CASP1 (ICE), CASP9, NOD1 (CARD4), PYCARD (TMS1/ASC), TNFRSF10A, TNFRSF10B (DR5), TP53. Caspase inhibitors: CD27 (TNFRSF7), XIAP (BIRC4).


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